Limonene is a terpene found in a large variety of plants, and is the major component in the oil of citrus fruit peels. After Myrcene, Limonene is the most abundant terpene found in most of the cannabis plants. In relation to cannabis and the entourage effect, Limonene is thought to activate synergies with several cannabinoids and other terpenes. Furthermore, it is known to facilitate the absorption of substances into the body, as it increases cell permeability.

Uses for Limonene include being used as a flavouring agent in food manufacture, in chemical synthesis as a precursor to carvone, and as a renewables-based solvent in cleaning products.